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Magnesium is an essential nutrient for plants and animals and is a natural constituent of fruits, vegetables, grain, meats and sea-foods. It is the fourth most abundant cation in the human body and the second most plentiful intracellularly. The average 60-kg human adult body contains about 24 g magnesium of which about one-half resides in bone. Although plasma levels vary between 1.7 and 3.0 mg per dl, very little is contained in extracellular fluid. Magnesium is essential for the production and transfer of energy, for protein, fat, and nucleic acid synthesis, for contractility in muscle and excitability in nerve, and for the activity of numerous enzyme systems.
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